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1

Persistence of locomotor-related interlimb reflex networks during walking after stroke

E. Paul Zehr, Pamela M. Loadman

Journal:

Clinical Neurophysiology

Year:

2012

Language:

english

File:

PDF, 1.45 MB

english, 2012

2

Pharmacokinetic Drug Interactions with Anticancer Drugs

Paul M. Loadman,Dr Mike C. Bibby

Journal:

Clinical Pharmacokinetics

Year:

1994

Language:

english

File:

PDF, 1.43 MB

english, 1994

3

Immunohistochemical analysis of NAD(P)H:quinone oxidoreductase and NADPH cytochrome P450 reductase in human superficial bladder tumours: Relationship between tumour enzymology and clinical outcome following intravesical mitomycin C therapy

Saurajyoti Basu, John E. Brown, G. Michael Flannigan, Jason H. Gill, Paul M. Loadman, Sandie W. Martin, Brian Naylor, Andrew J. Scally, Jill M. Seargent, Tariq Shah, Rajiv Puri, Roger M. Phillips

Journal:

International Journal of Cancer

Year:

2004

Language:

english

File:

PDF, 318 KB

english, 2004

4

Extraction of the synthetic lytic peptide, cecropin B, from biological fluid and analysis using reversed-phase high-performance liquid chromatography

Alison J. Moore, Paul M. Loadman, Deirdre A. Devine, Michael C. Bibby

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1995

Language:

english

File:

PDF, 483 KB

english, 1995

5

Total synthesis of largazole and analogues: HDAC inhibition, antiproliferative activity and metabolic stability

Hanae Benelkebir, Sabrina Marie, Annette L. Hayden, Jason Lyle, Paul M. Loadman, Simon J. Crabb, Graham Packham, A. Ganesan

Journal:

Bioorganic & Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 813 KB

english, 2011

6

Fluorescent 7-diethylaminocoumarin pyrrolobenzodiazepine conjugates: Synthesis, DNA interaction, cytotoxicity and differential cellular localization

Geoffrey Wells, Marie Suggitt, Marissa Coffils, Mirza A.H. Baig, Philip W. Howard, Paul M. Loadman, John A. Hartley, Terence C. Jenkins, David E. Thurston

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 212 KB

english, 2008

7

Separation methods for anthraquinone related anti-cancer drugs

Paul M Loadman, Christopher R Calabrese

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

2001

Language:

english

File:

PDF, 294 KB

english, 2001

8

Analysis of the imidazoacridinone C1311 by high-performance liquid chromatography

Christopher R. Calabrese, Paul M. Loadman

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1997

Language:

english

File:

PDF, 459 KB

english, 1997

9

Detergent addition to tryptic digests and ion mobility separation prior to MS/MS improves peptide yield and protein identification for in situ proteomic investigation of frozen and formalin-fixed paraffin-embedded adenocarcinoma tissue sections

Marie-Claude Djidja, Simona Francese, Paul M. Loadman, Chris W. Sutton, Peter Scriven, Emmanuelle Claude, Marten F. Snel, Julien Franck, Michel Salzet, Malcolm R. Clench

Journal:

Year:

2009

Language:

english

File:

PDF, 553 KB

english, 2009

10

Examination of the distribution of the bioreductive drug AQ4N and its active metabolite AQ4 in solid tumours by imaging matrix-assisted laser desorption/ionisation mass spectrometry

Sally J. Atkinson, Paul M. Loadman, Chris Sutton, Laurence H. Patterson, Malcolm R. Clench

Journal:

Rapid Communications in Mass Spectrometry

Year:

2007

Language:

english

File:

PDF, 233 KB

english, 2007

11

Method development for protein profiling in biological tissues by matrix-assisted laser desorption/ionisation mass spectrometry imaging

Marie-Claude Djidja, Vikki Carolan, Paul M. Loadman, Malcolm R. Clench

Journal:

Rapid Communications in Mass Spectrometry

Year:

2008

Language:

english

File:

PDF, 193 KB

english, 2008

12

Thio TEPA pharmacokinetics during intravesical chemotherapy and the influence of Tween 80

John R. W. Masters, Barbara J. McDermott, Wendy E. A. Jenkins, Elizabeth Fenwick, P. Julian R. Shah, Anthony R. Mundy, Paul M. Loadman, Michael C. Bibby

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1990

Language:

english

File:

PDF, 612 KB

english, 1990

13

Rhythmic arm cycling produces a non-specific signal that suppresses Soleus H-reflex amplitude in stationary legs

Pamela M. Loadman, E. Paul Zehr

Journal:

Experimental Brain Research

Year:

2007

Language:

english

File:

PDF, 442 KB

english, 2007

14

ThioTEPA pharmacokinetics during intravesical chemotherapy: the influence of dose and volume of instillate on systemic uptake and dose rate to the tumour

J. R. W. Masters, Barbara J McDermott, Stephen Harland, Michael C. Bibby, Paul M. Loadman

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1996

Language:

english

File:

PDF, 178 KB

english, 1996

15

Neural regulation of rhythmic arm and leg movement is conserved across human locomotor tasks

E. Paul Zehr, Jaclyn E. Balter, Daniel P. Ferris, Sandra R. Hundza, Pamela M. Loadman, Rebecca H. Stoloff

Journal:

The Journal of Physiology

Year:

2007

Language:

english

File:

PDF, 730 KB

english, 2007

16

An automated system for mapping spatial movement patterns in behavioral research

Paul Niswander, William Loadman, Kaye Rasnake, John Wells

Journal:

Behavior Research Methods

Year:

1994

Language:

english

File:

PDF, 1.01 MB

english, 1994

17

Preliminary pharmacokinetic and bioanalytical studies of SJG-136 (NSC 694501), a sequence-selective pyrrolobenzodiazepine dimer DNA-cross-linking agent

Gary P. Wilkinson, James P. Taylor, Steve Shnyder, Patricia Cooper, Phil W. Howard, David E. Thurston, Terence C. Jenkins, Paul M. Loadman

Journal:

Investigational New Drugs

Year:

2004

Language:

english

File:

PDF, 165 KB

english, 2004

18

Modification of the duocarmycin pharmacophore enables CYP1A1 targeting for biological activity

Pors, Klaus, Loadman, Paul M., Shnyder, Steven D., Sutherland, Mark, Sheldrake, Helen M., Guino, Meritxell, Kiakos, Konstantinos, Hartley, John A., Searcey, Mark, Patterson, Laurence H.

Journal:

Chemical Communications

Year:

2011

Language:

english

File:

PDF, 1.67 MB

english, 2011

19

Pharmacological and biological evaluation of a series of substituted 1,4-naphthoquinone bioreductive drugs

Roger M. Phillips, Mohammed Jaffar, Derek J. Maitland, Paul M. Loadman, Steven D. Shnyder, Gillian Steans, Patricia A. Cooper, Amanda Race, Adam V. Patterson, Ian J. Stratford

Journal:

Biochemical Pharmacology

Year:

2004

Language:

english

File:

PDF, 176 KB

english, 2004

20

Use of matrix-assisted laser desorption/ionisation mass spectrometry in cancer research

Hannah Bateson, Saira Saleem, Paul M. Loadman, Chris W. Sutton

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2011

Language:

english

File:

PDF, 837 KB

english, 2011

21

Pharmacological properties of a new aziridinylbenzoquinone, RH1 (2,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone), in mice

Paul M Loadman, Roger M Phillips, Lissa E Lim, Mike C Bibby

Journal:

Biochemical Pharmacology

Year:

2000

Language:

english

File:

PDF, 338 KB

english, 2000

22

Formation of DNA interstrand cross-links as a marker of Mitomycin C bioreductive activation and chemosensitivity

Milène Volpato, Jill Seargent, Paul M. Loadman, Roger M. Phillips

Journal:

European Journal of Cancer

Year:

2005

Language:

english

File:

PDF, 210 KB

english, 2005

23

Expression of matrix metalloproteinase-10 in human bladder transitional cell carcinoma

Jill M. Seargent, Paul M. Loadman, Sandie W. Martin, Brian Naylor, Michael C. Bibby, Jason H. Gill

Journal:

Year:

2005

Language:

english

File:

PDF, 339 KB

english, 2005

24

Synthesis and biological evaluation of colchicine C-ring analogues tethered with aliphatic linkers suitable for prodrug derivatisation

Fournier-Dit-Chabert, Jérémie, Vinader, Victoria, Santos, Ana Rita, Redondo-Horcajo, Mariano, Dreneau, Aurore, Basak, Ramkrishna, Cosentino, Laura, Marston, Gemma, Abdel-Rahman, Hamdy, Loadman, Paul M

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 551 KB

english, 2012

25

Re-engineering of the Duocarmycin Structural Architecture Enables Bioprecursor Development Targeting CYP1A1 and CYP2W1 for Biological Activity

Sheldrake, Helen M., Travica, Sandra, Johansson, Inger, Loadman, Paul M., Sutherland, Mark, Elsalem, Lina, Illingworth, Nicola, Cresswell, Alexander J., Reuillon, Tristan, Shnyder, Steven D., Mkrtchia

Journal:

Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 695 KB

english, 2013

26

Anti-colorectal cancer activity of an organometallic osmium arene azopyridine complex

Shnyder, Steve D., Fu, Ying, Habtemariam, Abraha, van Rijt, Sabine H., Cooper, Patricia A., Loadman, Paul M., Sadler, Peter J.

Journal:

Year:

2011

Language:

english

File:

PDF, 131 KB

english, 2011

27

Identification of Stage-Specific Breast Markers Using Quantitative Proteomics

Shaheed, Sadr-ul, Rustogi, Nitin, Scally, Andrew, Wilson, Julie, Thygesen, Helene, Loizidou, Maria A., Hadjisavvas, Andreas, Hanby, Andrew, Speirs, Valerie, Loadman, Paul, Linforth, Richard, Kyriacou,

Journal:

Journal of Proteome Research

Year:

2013

Language:

english

File:

PDF, 1.71 MB

english, 2013

28

A randomized controlled trial of eicosapentaenoic acid and/or aspirin for colorectal adenoma prevention during colonoscopic surveillance in the NHS Bowel Cancer Screening Programme (The seAFOod Polyp Prevention Trial): study protocol for a randomized controlled trial

Hull, Mark A, Sandell, Anna C, Montgomery, Alan A, Logan, Richard FA, Clifford, Gayle M, Rees, Colin J, Loadman, Paul M, Whitham, Diane

Journal:

Year:

2013

Language:

english

File:

PDF, 499 KB

english, 2013

29

Effect of Eicosapentaenoic Acid on E-type Prostaglandin Synthesis and EP4 Receptor Signaling Human Colorectal Cancer Cells

Hawcroft, Gillian, Loadman, Paul M., Belluzzi, Andrea, Hull, Mark A.

Journal:

Year:

2010

Language:

english

File:

PDF, 954 KB

english, 2010

30

MMP-10 Is Overexpressed, Proteolytically Active, and a Potential Target for Therapeutic Intervention in Human Lung Carcinomas

Gill, Jason H., Kirwan, Ian G., Seargent, Jill M., Martin, Sandie W., Tijani, Sidiq, Anikin, Vladimir A., Mearns, Alan J., Bibby, Michael C., Anthoney, Alan, Loadman, Paul M.

Journal:

Year:

2004

Language:

english

File:

PDF, 471 KB

english, 2004

31

Potentiation of EO9 anti-tumour activity by hydralazine

Bibby, Michael C., Sleigh, N. Ruth, Loadman, Paul M., Double, John A.

Journal:

European Journal of Cancer

Year:

1993

Language:

english

File:

PDF, 293 KB

english, 1993

32

Phase I/II Pilot Study of Intravesical Apaziquone (EO9) for Superficial Bladder Cancer

Puri, Rajiv, Palit, Victor, Loadman, Paul M., Flannigan, Michael, Shah, Tariq, Choudry, Guzanfar A., Basu, Saurajyoti, Double, John A., Lenaz, Gino, Chawla, Shanta, Beer, Mario, Van Kalken, Coen, de B

Journal:

The Journal of Urology

Year:

2006

Language:

english

File:

PDF, 318 KB

english, 2006

33

In vitro 3D colon tumor penetrability of SRJ09, a new anti-cancer andrographolide analog

Wong, Charng Choon, Periasamy, Nagarajan, Sagineedu, Sreenivasa Rao, Sidik, Shiran, Sumon, Shariful Hasan, Loadman, Paul, Phillips, Roger, Lajis, Nordin Haji, Stanslas, Johnson

Journal:

Investigational New Drugs

Year:

2014

Language:

english

File:

PDF, 772 KB

english, 2014

34

Cancer Therapy: Development of Novel Tumor-Targeted Theranostic Nanoparticles Activated by Membrane-Type Matrix Metalloproteinases for Combined Cancer Magnetic Resonance Imaging and Therapy (Small 3/2014)

Ansari, Celina, Tikhomirov, Grigory A., Hong, Su Hyun, Falconer, Robert A., Loadman, Paul M., Gill, Jason H., Castaneda, Rosalinda, Hazard, Florette K., Tong, Ling, Lenkov, Olga D., Felsher, Dean W.,

Journal:

Year:

2014

File:

PDF, 1.85 MB

2014

35

Tumor-Targeted Prodrug ICT2588 Demonstrates Therapeutic Activity against Solid Tumors and Reduced Potential for Cardiovascular Toxicity

Gill, Jason H., Loadman, Paul M., Shnyder, Steven D., Cooper, Patricia, Atkinson, Jennifer M., Ribeiro Morais, Goreti, Patterson, Laurence H., Falconer, Robert A.

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 2.08 MB

english, 2014

36

Probing cytochrome P450-mediated activation with a truncated azinomycin analogue

Vinader, Victoria, Sadiq, Maria, Sutherland, Mark, Huang, Mengying, Loadman, Paul M., Elsalem, Lina, Shnyder, Steven D., Cui, Hongjuan, Afarinkia, Kamyar, Searcey, Mark, Patterson, Laurence H., Pors,

Journal:

Year:

2015

Language:

english

File:

PDF, 689 KB

english, 2015

37

Current advances in the inhibition of the auto-regulatory interaction between the p53 tumour suppressor protein and MDM2 protein

Dart, Dafydd A, Mansoor, Maqsood S, Loadman, Paul M, Picksley, Steven M

Journal:

Expert Opinion on Therapeutic Patents

Year:

2001

Language:

english

File:

PDF, 188 KB

english, 2001

38

Development of Novel Tumor-Targeted Theranostic Nanoparticles Activated by Membrane-Type Matrix Metalloproteinases for Combined Cancer Magnetic Resonance Imaging and Therapy

Ansari, Celina, Tikhomirov, Grigory A., Hong, Su Hyun, Falconer, Robert A., Loadman, Paul M., Gill, Jason H., Castaneda, Rosalinda, Hazard, Florette K., Tong, Ling, Lenkov, Olga D., Felsher, Dean W.,

Journal:

Year:

2014

Language:

english

File:

PDF, 2.42 MB

english, 2014

39

Mucosal biomarkers of colorectal cancer risk do not increase at 6 months following sleeve gastrectomy, unlike gastric bypass

Kant, Prashant, Perry, Sarah L., Dexter, Simon P., Race, Amanda D., Loadman, Paul M., Hull, Mark A.

Journal:

Year:

2014

Language:

english

File:

PDF, 642 KB

english, 2014

40

Proteases in cancer drug delivery

Vandooren, Jennifer, Opdenakker, Ghislain, Loadman, Paul M., Edwards, Dylan R.

Journal:

Advanced Drug Delivery Reviews

Year:

2016

Language:

english

File:

PDF, 1.14 MB

english, 2016

41

Detection of (NAD(P)H:Quinone oxidoreductase-1, EC 1.6.99.2) 609C↷T and 465C↷T polymorphisms in formalin-fixed, paraffin-embedded human tumour tissue using PCR-RFLP

Phillips, Roger, Basu, Saurajyoti, Brown, John, Flannigan, G., Loadman, Paul, Martin, Sandie, Naylor, Brian, Puri, Rajiv, Shah, Tariq

Journal:

International Journal of Oncology

Year:

2004

Language:

english

File:

PDF, 1.63 MB

english, 2004

42

Targeting of Hypoxia in AQ4N-treated Tumour Xenografts by MALDIIon Mobility Separation-Mass Spectrometry Imaging

Djidja, Marie-Claude, Francese, Simona, Claude, Emmanuelle, Loadman, Paul, Sutton, Chris, Shynder, Steve, Cooper, Patricia, H Patterson, Laurence, A Carolan, Vikki, R. Clench, Malcolm

Journal:

Current Analytical Chemistry

Year:

2013

Language:

english

File:

PDF, 1.34 MB

english, 2013

43

Thin-layer chromatography/matrix-assisted laser desorption/ionisation mass spectrometry and matrix-assisted laser desorption/ionisation mass spectrometry imaging for the analysis of phospholipids in LS174T colorectal adenocarcinoma xenografts treated with

Batubara, Afnan, Carolan, Vikki A, Loadman, Paul M., Sutton, Chris, Shnyder, Steve D., Clench, Malcolm R.

Journal:

Rapid Communications in Mass Spectrometry

Year:

2015

Language:

english

File:

PDF, 2.32 MB

english, 2015

44

Applications of FT-NMR to Crosslink Density Determinations in Natural Rubber Blend Vulcanizates

Brown, Paul S., John, M., Loadman, R., Tinker, Andrew J.

Journal:

Rubber Chemistry and Technology

Year:

1992

File:

PDF, 667 KB

1992

45

Neuromechanical interactions between the limbs during human locomotion: an evolutionary perspective with translation to rehabilitation

Paul Zehr, E., Barss, Trevor S., Dragert, Katie, Frigon, Alain, Vasudevan, Erin V., Haridas, Carlos, Hundza, Sandra, Kaupp, Chelsea, Klarner, Taryn, Klimstra, Marc, Komiyama, Tomoyoshi, Loadman, Pamel

Journal:

Experimental Brain Research

Year:

2016

Language:

english

File:

PDF, 2.82 MB

english, 2016

46

Context-Dependent Modulation of Cutaneous Reflex Amplitudes during Forward and Backward Leg Cycling

Zehr, E. Paul, Hundza, Sandra R., Balter, Jaclyn E., Loadman, Pamela M.

Journal:

Year:

2009

Language:

english

File:

PDF, 1.22 MB

english, 2009

47

Measurement of red blood cell eicosapentaenoic acid (EPA) levels in a randomised trial of EPA in patients with colorectal cancer liver metastases

Watson, Henry, Cockbain, Andrew J., Spencer, Jade, Race, Amanda, Volpato, Milene, Loadman, Paul M., Toogood, Giles J., Hull, Mark A

Journal:

Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA)

Year:

2016

Language:

english

File:

PDF, 706 KB

english, 2016

48

Polysialic acid sustains cancer cell survival and migratory capacity in a hypoxic environment

Elkashef, Sara M., Allison, Simon J., Sadiq, Maria, Basheer, Haneen A., Ribeiro Morais, Goreti, Loadman, Paul M., Pors, Klaus, Falconer, Robert A.

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.26 MB

english, 2016

49

Estimated protective effectiveness of intramuscular immune serum globulin post-exposure prophylaxis during a measles outbreak in British Columbia, Canada, 2014

Bigham, Mark, Murti, Michelle, Fung, Christina, Hemming, Felicity, Loadman, Susan, Stam, Robert, Van Buynder, Paul, Lem, Marcus

Journal:

Year:

2017

Language:

english

File:

PDF, 282 KB

english, 2017

50

A liquid chromatography-tandem mass spectrometry method to measure fatty acids in biological samples

Volpato, Milene, Spencer, Jade A., Race, Amanda D., Munarini, Alessandra, Belluzzi, Andrea, Cockbain, Andrew J., Hull, Mark A., Loadman, Paul M.

Journal:

Journal of Chromatography B

Year:

2017

Language:

english

File:

PDF, 19.71 MB

english, 2017

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